Liberia Doctor treats Ebola With HIV Drug

Kundu and the other 12 patients who took the lamivudine and survived, received the drug in the first five days or so of their illness. The two patients who died received it between days five and eight. "I'm sure that when [patients] present early, this medicine can help," Logan said. "I've proven it right in my center." Logan is mindful that lamivudine can cause liver and other problems, but he says it's worth the risk since Ebola is so deadly. He also knows American researchers will say only a real study can prove effectiveness. That would involve taking a much larger patient population and giving half of them lamivudine and the other half a placebo. "Our people are dying and you're taking about studies?" he said. "It's a matter of doing all that I can do as a doctor to save some people's lives." Logan said he got the idea to try lamivudine when he read in scientific journals that HIV and Ebola replicate inside the body in much the same way. "Ebola is a brainchild of HIV," he said. "It's a destructive strain of HIV." At first he tried an HIV drug called acyclovir, but it didn't seem to be effective. Then he tried lamivudine on a healthcare worker who'd become ill, and within a day or two he showed signs of improvement and survived. Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases says that theoretically, Logan's approach has some merit. Lamivudine is a nucleocide analog, and other drugs in this class are being studied to treat Ebola.